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Hydroxychloroquine arm removed from RECOVERY trial

Oxford University have issued advice that hydroxychloroquine will no longer be given as part of the RECOVERY trial, as was reported in the The Guardian this week.


The RECOVERY trial was launched nationally in March. So far over 11000 patients have been recruited across 175 NHS hospitals in the UK.


Since then, a total of 1542 patients had been randomised to receive hydroxychloroquine, and 3132 patients were randomised to receive standard care.  Over 28 days, 25.7% of patients on hydroxychloroquine died, compared with 23.5% of those receiving standard care. P value = 0.10. This did not represent a statistically significant improvement in overall survival (OS).


The other arms of the RECOVERY trial remain available and recruitment is ongoing.


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